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Product Name
:
LACTOXAM-PLUS (dry powder)
Chemical Name
:
Ampicillin (Trihydrate)+Cloxacillin (Sodium) +Lactobacillus
Therapeutic Category
:
Antimicrobial
Pharmacologic Category
:
Antibiotic, Penicillin
Pharmaceutical Form
:
Dry powder
Composition
:
Ampicillin 125mg+Cloxacillin 125mg+Lactobacillus 30 million spores/5ml
Contraindications
Pregnancy
Lactation
Monitoring Parameters
Mechanism of Action
Pharmacodynamics / Kinetics
Dosing
 
Syrup CHILDREN : - Up to 2 years : 1 teaspoon (2.5 ml) each 6 hours, to be given 30 minutes before meals. - From 2 - 10 years : teaspoon (5 ml) each 6 hours, 30 minutes before meals or 25-50 mg/kg of body weight per day.
Capsules : ADULTS : One capsules (500 mg) each 6 hours should be given 30 minutes before meals.
Use
 
It is used in the treatment of : - Upper and Lower respiratory tract infections ( Tonsillitis, Sinusitis, Pneumonia, Bronchitis ). - Genitourinary tract infections ( Cystitis, Pyelonephritis, Urethritis). - Skin and soft tissue infections ( carbuncles )
Adverse Reactions
 
Diarrhoea side effects due to antibiotics are minimized by the presence of Lactobacillus Sporogene. It may cause : skin rashes, pruritus, nausea, vomiting, neutropenia, eosinophillia and rarely hepatitis.
Warnings / Precautions Drug
 
LACTOXAM Plus should be given with caution : - In patients with history of allergy, lymphocytic leukaemia and renal failure. - Treatment should be discontinued, if a skin rash occurs.
Interactions
 
Probenecid reduces the excretion of LACTOXAM Plus. An increased frequency of skin rashes in patients receiving LACTOXAM Plus with allopurinol. LACTOXAM Plus may decrease the efficacy of oestrogen-containing oral contraceptives
 
   
 
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