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Product Name
LACTOXAM-PLUS (dry powder)
Chemical Name
Ampicillin (Trihydrate)+Cloxacillin (Sodium) +Lactobacillus
Therapeutic Category
Pharmacologic Category
Antibiotic, Penicillin
Pharmaceutical Form
Dry powder
Ampicillin 125mg+Cloxacillin 125mg+Lactobacillus 30 million spores/5ml
Monitoring Parameters
Mechanism of Action
Pharmacodynamics / Kinetics
Syrup CHILDREN : - Up to 2 years : 1 teaspoon (2.5 ml) each 6 hours, to be given 30 minutes before meals. - From 2 - 10 years : teaspoon (5 ml) each 6 hours, 30 minutes before meals or 25-50 mg/kg of body weight per day.
Capsules : ADULTS : One capsules (500 mg) each 6 hours should be given 30 minutes before meals.
It is used in the treatment of : - Upper and Lower respiratory tract infections ( Tonsillitis, Sinusitis, Pneumonia, Bronchitis ). - Genitourinary tract infections ( Cystitis, Pyelonephritis, Urethritis). - Skin and soft tissue infections ( carbuncles )
Adverse Reactions
Diarrhoea side effects due to antibiotics are minimized by the presence of Lactobacillus Sporogene. It may cause : skin rashes, pruritus, nausea, vomiting, neutropenia, eosinophillia and rarely hepatitis.
Warnings / Precautions Drug
LACTOXAM Plus should be given with caution : - In patients with history of allergy, lymphocytic leukaemia and renal failure. - Treatment should be discontinued, if a skin rash occurs.
Probenecid reduces the excretion of LACTOXAM Plus. An increased frequency of skin rashes in patients receiving LACTOXAM Plus with allopurinol. LACTOXAM Plus may decrease the efficacy of oestrogen-containing oral contraceptives
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